Introduction to i2b2

Fall 2026

Piyush Chaudhari | Qian Li

2026-08-28

i2b2

Fig 1. i2b2 Star Schema

• i2b2 is Informatics for Integrating Biology & the Bedside Cohort Discovery System
• i2b2 is an NIH-funded National Center for Biomedical Computing (NCBC) based at Partners’ HealthCare System in Boston
• Enables investigators to identify potential study cohorts using clinical data resources
• Intended for protocol development for grant or IRB submission
• Provides access to curated data through a web client
• Returns only patient counts

i2b2 Community Webpage

Feasibility and Cohort Discovery

• How many men with hypertension diagnoses had at least one inpatient encounter between January and December 2018?​
• How many women ages 45-65 had successful breast cancer surgery?​
• How many children were diagnosed with diabetes and had Hemoglobin A1c greater than 7% in the same financial encounter?​

Data Availability in i2b2

• i2b2 data guide​

  • Go to UF Health IDR i2b2 training page here​

  • Click on The i2b2 Data Guide

• Data is refreshed quarterly, starting June 2011​
• Data is represented as closely as possible to the original source​ in the i2b2 Common Data Model

i2b2 Client Demo

UF Health i2b2 Webclient